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Schizophrenia _ types
The
schizophrenic disorders are characterized in general by
fundamental and characteristic distortions of thinking and
perception, and by inappropriate or blunted affect. Clear
consciousness and intellectual capacity are usually maintained,
although certain cognitive deficits may evolve in the course of
time. The disturbance involves the most basic functions that
give the normal person a feeling of individuality, uniqueness,
and self-direction.
The most intimate
thoughts, feelings, and acts are often felt to be known to or
shared by others, and explanatory delusions may develop, to the
effect that natural or supernatural forces are at work to
influence the afflicted individual's thoughts and actions in
ways that are often bizarre.
The individual may see himself or herself as the pivot of all
that happens. Hallucinations, especially auditory, are common
and may comment on the individual's behavior or thoughts.
Perception is
frequently disturbed in other ways: colors or sounds may seem
unduly vivid or altered in quality, and irrelevant features of
ordinary things may appear more important than the whole object
or situation.
Perplexity is also
common early on and frequently leads to a belief that everyday
situations possess a special, usually sinister, meaning intended
uniquely for the individual. In the characteristic schizophrenic
disturbance of thinking, peripheral and irrelevant features of a
total concept, which are inhibited in normal directed mental
activity, are brought to the fore and utilized in place of those
that are relevant and appropriate to the situation.
Thus thinking becomes vague, elliptical, and obscure, and its
expression in speech sometimes incomprehensible. Breaks and
interpolations in the train of thought are frequent, and
thoughts may seem to be withdrawn by some outside agency.
Mood is
characteristically shallow, capricious, or incongruous.
Ambivalence and disturbance of volition may appear as inertia,
negativism, or stupor. Catatonia may be present. The onset may
be acute, with seriously disturbed behavior, or insidious, with
a gradual development of odd ideas and conduct.
The course of the disorder shows equally great variation and is
by no means inevitably chronic or deteriorating (the course is
specified by five-character categories). In a proportion of
cases, which may vary in different cultures and populations, the
outcome is complete, or nearly complete, recovery.
The sexes are approximately equally affected by the onset tends
to be later in women.
Although no
strictly pathognomonic symptoms can be identified, for practical
purposes it is useful to divide the above symptoms into groups
that have special importance for the diagnosis and often occur
together, such as:
(a) Thought echo, thought insertion or withdrawal, and thought
broadcasting;
(b) Delusions of control, influence, or passivity, clearly
referred to body or limb movements or specific thoughts,
actions, or sensations; delusional perception;
(c) Hallucinatory voices giving a running commentary on the
patient's behaviour, or discussing the patient among themselves,
or other types of hallucinatory voices coming from some part of
the body;
persistent delusions of other kinds that are culturally
inappropriate and completely impossible, such as religious or
political identity, or superhuman powers and abilities (e.g.
being able to control the weather, or being in communication
with aliens from another world);
(e) Persistent hallucinations in any modality, when accompanied
either by fleeting or half-formed delusions without clear
affective content, or by persistent over-valued ideas, or when
occurring every day for weeks or months on end;
(f)Breaks or interpolations in the train of thought, resulting
in incoherence or irrelevant speech, or neologisms;
(g) Catatonic behaviour, such as excitement, posturing, or waxy
flexibility, negativism, mutism, and stupor;
(h) "negative" symptoms such as marked apathy, paucity of
speech, and blunting or incongruity of emotional responses,
usually resulting in social withdrawal and lowering of social
performance; it must be clear that these are not due to
depression or to neuroleptic medication;
(i) a significant and consistent change in the overall quality
of some aspects of personal behaviour, manifest as loss of
interest, aimlessness, idleness, a self-absorbed attitude, and
social withdrawal.
Diagnostic Guidelines
The normal requirement for a diagnosis of schizophrenia is that
a minimum of one very clear symptom (and usually two or more if
less clear-cut) belonging to any one of the groups listed as (a)
to (d) above, or symptoms from at least two of the groups
referred to as (e) to (h), should have been clearly present for
most of the time during a period of 1 month or more.
Conditions meeting such symptomatic requirements but of
duration less than 1 month (whether treated or not) should be
diagnosed in the first instance as acute schizophrenia-like
psychotic disorder and are classified as schizophrenia if the
symptoms persist for longer periods.
Viewed
retrospectively, it may be clear that a prodromal phase in which
symptoms and behaviour, such as loss of interest in work, social
activities, and personal appearance and hygiene, together with
generalized anxiety and mild degrees of depression and
preoccupation, preceded the onset of psychotic symptoms by weeks
or even months.
Because of the
difficulty in timing onset, the 1-month duration criterion
applies only to the specific symptoms listed above and not to
any prodromal nonpsychotic phase. The diagnosis of schizophrenia
should not be made in the presence of extensive depressive or
manic symptoms unless it is clear that schizophrenic symptoms
antedated the affective disturbance.
If both
schizophrenic and affective symptoms develop together and are
evenly balanced, the diagnosis of schizoaffective disorder
should be made, even if the schizophrenic symptoms by themselves
would have justified the diagnosis of schizophrenia.
Schizophrenia should not be diagnosed in the presence of overt
brain disease or during states of drug intoxication or
withdrawal.
Paranoid Schizophrenia
This is the commonest type of schizophrenia in most parts of the
world. The clinical picture is dominated by relatively stable,
often paranoid, delusions, usually accompanied by
hallucinations, particularly of the auditory variety, and
perceptual disturbances. Disturbances of affect, volition, and
speech, and catatonic symptoms, are not prominent.
Examples of the
most common paranoid symptoms are:
(a) delusions of persecution, reference, exalted birth, special
mission, bodily change, or jealousy;
(b) hallucinatory voices that threaten the patient or give
commands, or auditory hallucinations without verbal form, such
as whistling, humming,orlaughing;
(c) hallucinations of smell or taste, or of sexual or other
bodily sensations; visual hallucinations may occur but are
rarely predominant.
Thought disorder
may be obvious in acute states, but if so it does not prevent
the typical delusions or hallucinations from being described
clearly.
Affect is usually less blunted than in other varieties of
schizophrenia, but a minor degree of incongruity is common, as
are mood disturbances such as irritability, sudden anger,
fearfulness, and suspicion.
"Negative" symptoms such as blunting of affect and impaired
volition are often present but do not dominate the clinical
picture.
The course of paranoid schizophrenia may be episodic, with
partial or complete remissions, or chronic. In chronic cases,
the florid symptoms persist over years and it is difficult to
distinguish discrete episodes. The onset tends to be later than
in the hebephrenic and catatonic forms.
Diagnostic Guidelines
The general criteria for a diagnosis of schizophrenia must be
satisfied. In addition, hallucinations and/or delusions must be
prominent, and disturbances of affect, volition and speech, and
catatonic symptoms must be relatively inconspicuous.
The hallucinations will usually be of the kind described in (b)
and (c) above. Delusions can be of almost any kind of delusions
of control, influence, or passivity, and persecutory beliefs of
various kinds are the most characteristic. inludes:
* paraphrenic schizophrenia
Differential
diagnosis.
It is important to exclude epileptic and drug-induced
psychoses, and to remember that persecutory delusions might
carry little diagnostic weight in people from certain countries
or cultures.
Hebephrenic Schizophrenia
A form of schizophrenia in which affective changes are
prominent, delusions and hallucinations fleeting and
fragmentary, behavior irresponsible and unpredictable, and
mannerisms common.
The mood is shallow and inappropriate and often accompanied by
giggling or self-satisfied, self-absorbed smiling, or by a lofty
manner, grimaces, mannerisms, pranks, hypochondria cal
complaints, and reiterated phrases.
Thought is disorganized and speech rambling and incoherent.
There is a tendency to remain solitary, and behavior seems empty
of purpose and feeling. This form of schizophrenia usually
starts between the ages of 15 and 25 years and tends to have a
poor prognosis because of the rapid development of "negative"
symptoms, particularly flattening of affect and loss of
volition.
In addition,
disturbances of affect and volition, and thought disorder are
usually prominent. Hallucinations and delusions may be present
but are not usually prominent.
Drive and determination are lost and goals abandoned, so that
the patient's behavior becomes characteristically aimless and
empty of purpose.
A superficial and mannerist preoccupation with religion,
philosophy, and other abstract themes may add to the listener's
difficulty in following the train of thought.
Diagnostic Guidelines
The general criteria for a diagnosis of schizophrenia must be
satisfied. Hebephrenic should normally be diagnosed for the
first time only in adolescents or young adults. The premorbid
personality is characteristically, but not necessarily, rather
shy and solitary.
For a confident diagnosis of hebephrenic, a period of 2 or 3
months of continuous observation is usually necessary, in order
to ensure that the characteristic behaviors described above are
sustained.
Catatonic Schizophrenia
Prominent psychomotor disturbances are essential and dominant
features and may alternate between extremes such as hyperkinesis
and stupor, or automatic obedience and negativism.
Constrained attitudes and postures may be maintained for long
periods. Episodes of violent excitement may be a striking
feature of the condition.
For reasons that are poorly understood, catatonic schizophrenia
is now rarely seen in industrial countries, though it remains
common elsewhere.
These catatonic phenomena may be combined with a dream-like
(aneroid) state with vivid scenic hallucinations.
Diagnostic Guidelines
The general criteria for a diagnosis of schizophrenia must be
satisfied.
Transitory and isolated catatonic symptoms may occur in the
context of any other subtype of schizophrenia, but for a
diagnosis of catatonic schizophrenia one or more of the
following behaviors should dominate the clinical picture:
a) Stupor (marked decrease in reactivity to the environment and
in spontaneous movements and activity) or mutism;
(b) Excitement (apparently purposeless motor activity, not
influenced by external stimuli);
(c) posturing (voluntary assumption and maintenance of
inappropriate or bizarre postures)
(d) Negativism (an apparently motiveless resistance to all
instructions or attempts to be moved, or movement in the
opposite Direction
(e) Rigidity (maintenance of a rigid posture against efforts to
be moved)
(f) Waxy flexibility (maintenance of limbs and body in
externally imposed positions);
(f) Other symptoms such as command automatism (automatic
compliance with instructions), and preservation of words and
phrases.
In uncommunicative patients with behavioral manifestations of
catatonic disorder, the diagnosis of schizophrenia may have to
be provisional until adequate evidence of the presence of other
symptoms is obtained. It is also vital to appreciate that
catatonic symptoms are not diagnostic of schizophrenia. A
catatonic symptom or symptoms may also be provoked by brain
disease, metabolic disturbances, or alcohol and drugs, and may
also occur in mood disorders.
Undifferentiated Schizophrenia
Conditions meeting the general diagnostic criteria for
schizophrenia
But not conforming to any of the above subtypes, or exhibiting
the features of more than one of them without a clear
predominance of a particular set of diagnostic characteristics.
This rubric should be used only for psychotic conditions (i.e.
residual schizophrenia and post-schizophrenic depression are
excluded) and after an attempt has been made to classify the
condition into one of the three preceding categories.
Diagnostic Guidelines
This
category should be reserved for disorders that:
(a) Meet the diagnostic criteria for schizophrenia
(b) do not satisfy the criteria for the paranoid, hebephrenic,
or catatonicsubtypes;
(c) do not satisfy the criteria for residual schizophrenia or
post- schizophrenic depression.
Post-Schizophrenic Depression
A depressive episode, which may be prolonged, arising in the
aftermath of a schizophrenic illness.
Some schizophrenic symptoms must still be present but no longer
dominate the clinical picture. These persisting schizophrenic
symptoms may be "positive" or "negative", though the latter are
more common. It is uncertain, and immaterial to the diagnosis,
to what extent the depressive symptoms have merely been
uncovered by the resolution of earlier psychotic symptoms
(rather than being a new development) or are an intrinsic part
of schizophrenia rather than a psychological reaction to it.
They are rarely
sufficiently severe or extensive to meet criteria for a severe
depressive episode, and it is often difficult to decide which of
the patient's symptoms are due to depression and which to
narcoleptic medication or to the impaired volition and affective
flattening of schizophrenia itself. This depressive disorder is
associated with an increased risk of suicide.
Diagnostic Guidelines
The diagnosis should be made only if:
(a) the patient has had a schizophrenic illness meeting the
general criteria for schizophrenia
(b) within the past 12 monthssome schizophrenic symptoms are
still present;
(c) the depressive symptoms are prominent and distressing,
fulfilling at least the criteria for a depressive episode, and
have been present for at least 2 weeks.
If the patient no longer has any schizophrenic symptoms, a
depressive episode should be diagnosed. If schizophrenic
symptoms are still florid and prominent, the diagnosis should
remain that of the appropriate schizophrenic subtype.
Residual Schizophrenia
A chronic stage in the development of a schizophrenic disorder
in which there has been a clear progression from an early stage
(comprising one or more episodes with psychotic symptoms meeting
the general criteria for schizophrenia described above) to a
later stage characterized by long-term, though not necessarily
irreversible, "negative" symptoms.
Diagnostic Guidelines
For a confident diagnosis, the following requirements should be
met:
(a) prominent "negative" schizophrenic symptoms, i.e.
psychomotor slowing, under activity, blunting of affect,
passivity and lack of initiative, poverty of quantity or content
of speech, poor nonverbal communication by facial expression,
eye contact, voice modulation, and posture, poor self-care and
social performance;
(b) evidence in the past of at least one clear-cut psychotic
episode meeting the diagnostic criteria for schizophrenia;
(c) a period of at least 1 year during which the intensity and
frequency of florid symptoms such as delusions and
hallucinations have been minimal or substantially reduced and
the "negative" schizophrenic syndrome has been present;
(d) absence of dementia or other organic brain disease or
disorder, and of chronic depression or institutionalism
sufficient to explain the negative impairments.
If adequate
information about the patient's previous history cannot be
obtained, and it therefore cannot be established that criteria
for schizophrenia have been met at some time in the past, it may
be necessary to make a provisional diagnosis of residual
schizophrenia
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