Definition
Materia medica = Medical material in latin
Homoeopathic materia medica = A record of the pathogenetic effects of medicines(Hughes), derived primarily from proving the drug on healthy human beings, supplemented by noting effects of its overdosing and toxicity, and clinical symptoms during its application on the sick.
Nature of Materia Medica – Aph 143-144
True Materia medica defined in aphorism - 143
Pure Materia Medica (free from speculation) in aphorism – 144

Drug Proving
Drug proving in aphorism – 105-144
Human experiments before Hahnemann - mentioned by Albrecht Von Haller
Experimented by Stork (1750-60) / Alexander (1768)
Dose in proving aph 128- 4-6 small globules of 30th on empty stomach daily, for several days, till alteration of health is conspicuous
Observations on sick can be included - aph 142
Hyganthropharmacology – Human provings (James Stephenson)

Sources
Sources of remedies - Animal / Plant/ Mineral / Nosode / Sarcode / Imponderablia
Sources of symptoms - Proving, Toxicology / overdosing, Animal experimentation, Observation on sick & clinical experience

Source books
Fragmenta de viribus medicamentorum positivus sive in sano corpore humano observatis ( Latin) = Fragments on the Positive Powers of Drugs, - that is to say, their effects observed in the healthy body
Dose - “one pretty strong dose”
Published 1805, 27 drugs (22 MMP + 2 CD carried forward)

Reine arzneimittellehre (German) = Materia Medica Pura (Latin), 6 volumes
1st ed. 6 vols – 1811–1821(11/16/17/18/19/21)
2nd ed. 6 vols – 1822-27 (22/24/25/25/26/27)
3rd ed. 2 Vols – 1830, 33
Present ed. 2 Vols (Translation 1880) – 3rd ed. of Vol 1 & 2, and 2nd ed. of Vol 3 – 6
Translated by RE Dudgeon Annotation by R Hughes
Total no. of drugs – 67 (22 Fragmenta + 45 new) (1st ed. = 65 (Hep omitted by Hughes, says 61 + magnets), Vol 1 = 12 drugs, 2nd ed. = 1st + Ambr, CA, CV in Vol 6, 3rd ed. – Caust shifted)
Fellow provers – 37
Hahnemann's symptom - No name or sign attached
Doubtful symptoms in brackets
Clinical symptom - "curative action" (Hughes - "Principles")
Mental symptoms from Langhammer suspect
Symptoms from Provings by Hahnemann / Fellow provers, poisoning / overdosing (citation from authors), observations on the sick
Dose - Tincture / Ist trituration to 30th in III ed.

Die Chronischen Krankheiten (German) = Chronic Diseases
First ed. Vol I – III 1828, Vol IV 1830 Second ed. Vol I – V 1835-39
Translation (1896)- Prof Louis H Tafel Annotation - Dr. R Hughes Editor – Pemberton Dudley
No of drugs = 47 (2 Fragmenta + 17 MMP + 28 new, 30 not in MMP) (1st ed. = 17 new + 5 MMP) (2nd ed. = 11 new + 2 Fragmenta + 12 MMP + 22 1st ed.)
Fellow provers = 1st ed., nil 2nd ed. 26 (New except Whale)
Symptoms from sources of MMP, proving (Fellow provers), other published provings (Hartlaub & trinks, Stapf, Professor Joerg), Observations on sick (Hahnemann - Fresh sensation + aggravations)
Nenning's symptoms - Nenning was an austrian surgeon, contributed to Hartlaub & Trinks MM, only initials of his name was given in proving. Hahnemann questioned, Hering clarified later as trustworthy.
Dose (Hahnemann’s) – 1st ed. -" violent effects " of the attenuations from the second to the twelfth, experienced by the sufferers from chronic disease 2nd ed. – 6th to 30th

The Encyclopedia of Pure Materia Medica - TF Allen
Vol 10 + 2 (index = "Symptom register") Year - 1874
Total - 1039 drugs
Symptoms from - Same as CD / MMP + few clinical symptoms - designated by a small cipher “”
Ordinary type / Italics (repeatedly observed) / Star with italics / Star with bold face (Repeatedly verified) / Toxicology "t"
Symptoms are referenced to source and circumstances of symptoms, hence can be traced
Other books by TF Allen - Hand book of Materia Medica and Homoeopathic Therapeutics, A Primer of Materia Medica

The Guiding Symptoms of our Materia Medica - C Hering
Vol 10 year 1879 - 1891 Hering died after completing part of Vol III
Total No. of drugs - 410 Each described under 48 sub sections
5 grades - occasionally confirmed (ı), Frequently confirmed (ıı), Verified by cures (ıı), Repeatedly verified (ıı) and approved characteristic (☞)
Other notations -  (Pathological / physiological condition), Three vertical dots (Observations from old /new school), π (observed only on sick, while under medicinal action) and "t" (toxicological)
Other books by Hering – Condensed Materia Medica, Homoeopathic Domestic Physician

Cyclopedia of Drug Pathogenesy - R Hughes & JP Dake
Vols - 4 Year - 1886 - 1891
Proving Symptoms not in schema, but narrative, in order of occurrence (“Materia medica starts with vertigo and ends with confusion” – Hughes)
Animal experiments & poisonings included
Discards provings less than two people, observations in sick and potencies above 12th unless corroborated by lower potencies

Other sources
Special Symptomatology of the New Remedies – Hale EM
Dictionary of Homoeopathic Materia Medica of 131 New Homoeotherapeutics - OA Julian


Other Materia Medicae
Key Notes
Keynotes and Characteristics with Comparisons – Allen HC
Keynotes of The Materia Medica - Guernsey H. N
Keynotes of The Homoeopathic Materia Medica – A Von Lippe
Keynotes And Red Line Symptoms of The Materia Medica - A Von Lippe
A Synoptic key of the Materia Medica – Boger CM

Comparative Materia Medica
Comparative Materia Medica - RH Gross
Comparative Materia Medica - EA Farrington
The Study Of Remedies By Comparison – HA Roberts

Clinical Materia Medica
Clinical Materia Medica - Farrington E. A.
Pocket Manual of Homeopathic Materia Medica – Boericke W
A Manual of Materia Medica Therapeutics and Pharmacology - Blackwood AL
Physiological Materia Medica – WH Burt
Text Book of Materia Medica with Therapeutics - Cowperthwaite
Materia Medica of Homoeopathic Medicines – Phatak

Descriptive Materia Medica
Lectures on Homoeopathic Materia Medica – Kent JT
Homoeopathic Drug Pictures - ML Tyler
A study on Materia Medica - NM Choudhuri
A dictionary of Practical Materia Medica (3 vols) - JH clarke year – 1900 (other - The Prescriber, Clinical Repertory)
A Manual of Homoeopathic Therapeutics - EA Neatby & TG Stonham
Lectures on Materia Medica – Dunham C
Plain Talks on Materia Medica with Comparisons - WI Pierce

Minerals
Text book of Homoeoapthic Materia Medica - Otto Leeser

Nosodes
The Materia Medica of Some Important Nosodes - Allen HC
Materia Medica of Nosodes – OA Julian

Indian
Drugs of Hindusthan - Ghosh

Other
New old and forgotten Remedies – Anschultz EP
Special Symptomatology of the New Remedies – Hale EM
Special Therapeutics of the new remedies - Hale EM
Systematic Materia Medica of Homoeopathic Remedies - KN Mathur
Homoeopathic Materia Medica of Graphic drug pictures and Clinical Comments - Pulford
Essentials of Homeopathic Materia Medica - Dewey W. A
The carcinosin Drug Picture - Foubister D. M.
“Homoeopathic milk for allopathic babies” – A Manual of Pharmacodynamics – R Hughes

Provers / Authorities
Hahnemann
Total Provings published by Hahnemann – as per Hughes 66 (MMP) + 30 (CD) + 3 (Fragmenta unpublished) = 99
Actual - 67 (MMP) + 30 (CD) + 3 (Fragmenta) = 100

Acon, Alum, Am-c, Arg-m, Arn, Ars, Aur, Bar-c, Bell, Bism, Borx, Bry, Calc, Camph, Cann-s, Canth, Caps, Carb-v, Carb-ac, Caust, Cham, Chel, Cic, Cina, Chin, Clem, Cocc, Coff, Coloc, Con, Cupr, Cycl, Dig, Dros, Dulc, Eup-per, Euph, Ferr, Graph, Hell, Hep, Hyos, Ign, Iod, Ip, Kali-c, Led, Lyc, Mag-c, Mag-m, Meny, Mag-p, Merc, Mosch, Mur-ac, Nat-c, Nat-m, Nit-ac, Nux-v, Op, Petr, Ph-ac, Phos, Puls, Rheum, Rhus-t, Ruta, Sabad, Samb, Sars, Sep, Sil, Spig, Spong, Stann, Staph, Stram, Sulph, Thuj, Valer, Verat

Hering
All-c, Brom, Calc-ar, Calc-p, Calc-s, Crot-h, Fl-ac, Glon, Ham, Hyper, Kalmia, Lach, Lith-c, Lyss, Meph, Psor, Sel, Ther

Stapf
Anac, Agar, Ant-t, Colch, Croc, Mez, Plat, Sabin, Teucr

Burt
Caul, Coll, Dios, Erig, Ust, Verat-v

Swan
Lac-c, Lac-d, Med, Syph, Variolinum, Vaccininum

Hale EM
Gels, Hydr, Phyt

Nenning
Aeth, Am-m, Mill

Petroz
Actea-sp, Murex, Aster

Burnett
Bacill, Bellis-p, Urtica, Cundurango

HC Allen
Kali-p, Sec, Viburnum

TF Allen
Amyl-nit, Pic-ac

Drysdale - Kali-bi, Pyrog Nunez - Tarent Russel & Stokes – Naja
Rubini - Cactus Caspari - Ant-c Farrington - Nat-p Clotar Muller - Coca Dr. Ray (Calcutta) - Blatta-o Clarke - Rad-br DM Foubister - Carc
Mure – Elaps cor, Bufo

First proving of nosode – Psor by Hahnemann (Clarke)

                        
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