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Skin, the mirror
of internal man is the largest organ of our body, consisting
about 1.7m2 in surface area and 4 kg of body weight. it is the
major interface between the man and his environment. Dermatology
the science of skin disease is a visual clinical specialty.
As far as homoeopathic physicians are concerned the study of
skin diseases are very important, because skin is one of the
most important site of action of our medicines.
In repertory of homoeopathic materia medica by
Dr. J.T.Kent we
perceives numerous dermatological problems of which some are
expressed in old terminologies, if we understood the exact
meaning of these terms, it will be great help in the selection
of exact similimum .In this work my intention is to investigate
through the deeper aspect of skin in kent’s repertory.
FUNCTIONS OF
SKIN:-
1) Protection against water loss (sc)
2) Protection against water gain.(sc)
3) Protection against penetration of toxic substances.
4) Protection against microbial attack.
5) Thermal regulation through heat loss, via
(a) Sweat evaporation and
(b) Vasomotor regulation.
6) Communication through sensory massage.
7) Immune function with a role in protection against foreign
antigen.
8) Metabolic function with an important role in synthesis of Vit
D after solar UV radiation.
CLASSIFICATION
OF SKIN DISORDERS .
Skin disorders may either be generalised, affecting all part of
the integument, localized to one or several sites. The site of
abnormality is known as a lesion. Or they may be eruptive (exanthematic)
in which large number of lesions appear spottily over the skin.
CLASSIFICATION
BASED ON THE ELEMENTERY LESIONS: -
{1} MACULE.
CONDITIONS: -
(a) Erythema.
(b) Rosacea.
(c) Lupus.
(d) Chloasma
(e) Xanthelasma.
(f) Syphilis.
(g) Purpura.
(h) Naevus.
(i) Lenigo Maligna.
(j) Leucoderma.
(k) Roseola.
{2} VESICLE.
CONDITIONS,
(a) Eczema.
(b) Erysipelas
(c) Herpes.
(d) Impetigo contagiosa.
(e) Erythema multiforme.
(f) Scabies.
(g) Sudamina.
(h) Varicella.
(i) Zoster.
{3} BULLA.
CONDITIONS,
(a) Erysepelas.
(b) Leprosy.
(c) Pemphigus.
(d) Rupia.
{4} PUSTULE.
CONDITIONS,
(a) Acne.
(b) Ecthyma.
(c) Eczema.
(d) Furuncles.(Boils)
(e) Scabies.
(f) Sphilis.
(g) Variola.
(i) Dermatitis multiforme.
{5} PAPULE.
CONDITIONS,
Acne
Erythema multiforme
Eczema
Lichen plannus
Lichen simplex
Lupus
Milium
Molluscum
Prurigo
Rubiola
Scabies
Syphilis
Urticaria
Variola
{6} TUBERCLE
(a) Acne
(b) Fibroma
(c) Lentigo maligna
(d) Leprosy
(e) Lupus
(f) Syphilis
(g) Morphoea
{7} SCALES.
(a) Icthyiosis
(b) Pityriasis simplex
(c) Pityriasis Verscicolor
(d) Psoriasis
(e) Syphilis
(f) Tricophytosis capitis
(g) Eczema
(h) Lupus erythematosis
[1] MACULE
Localized lesion no more than discoloration of skin, with out
any secretion, effusion, and change in thickness. It may be
black from increase of pigment Or white from loss of pigment or
red from congestion.
Rubric; In kents repertory we can't get the rubric macule
so we can take
Skin, Discoloration, also in location chapters
Conditions:-
a) ERYTHEMA.
Rubric:-
Skin
Eruption, nodular,rosy(erythema)
Almost all conditions comes under immunologically mediated skin
disorders.
E.g.:- Erythema multiforme
Erythema nodosum.
1) ERYTHEMA MULTIFORME.
An acute and relatively short lived inflammatory reaction of
skin and mucosae occurring in response to a variety of antigenic
stimuli resulting in scattered lesions in dermoepidermal
junction
C/F :Red to purple macular papules some of which become annular:
Face and upper limb commonly affected. Front of mouth is eroded
and sloughy. Disorder starts acutely and usually over in less
than two weeks. Etiology unknown. Disorder may be precipitated
by infections like: Herpes simplex , coccidio mycosis,
Histoplasmosis etc.
ERYTHEMA NODOSUM
A painful inflammatory disorder in which crops of tender nodules
occurs in response to antigenic stimuli.
C/F: Individual lesions are red, raised and tender, varying in
size from 1 to 3cm in diameter. Occurs in crops on shin, less
common in forearm. Lesion takes two to six weeks to resolve.
Disorder may be precipated by infections like : Tuberculosis,
Sarcoidosis, Brucellosis, Leprosy.
B] CHLOASMA.
Macule is somewhat diffuse occurring in forehead and cheeks and
is of brown colour. These changes in degree of pigmentation
common in pregnancy. Dark areas appear symmetrically, across the
cheeks ,around the eyes , over forehead giving a mask like
appearance.
Rubric; no direct rubric.
We can take Face, Discoloration, brown spots
Forehead spots etc.
[C] XANTHELASMA.
Lesion appears as a papule around eyes, not associated with
hyperlipidemia in 60-70 % of cases.
Rubric; Face eruption, lids on.
[D] ROSACEA (Rosy macule)
Is a chronic inflammatory lesions of face.Characterised by
persistent erythema and talangectasia punctuated by acute
episodes of swelling and papule. Papules are red, dome shaped
and nontender in contrast to Acne. Common in cheek, forehead,
nose and chin.
Rubric; Face,Eruption,Acne,rosacea.
[E] LUPUS VULGARIS.
Is a rare slowly progressive granulomatous plaque on skin caused
by tubercle bacilli. Often has a thickened psoriasiform
appearance but blanching with a glass slide will reveal gray
green foci due to underlying granulomatous inflammation.(apple
jelly nodules)
Rubric; Skin ,Lupus.
[F] SYPHILIS.
This disease caused by Trepanema pallidum. Reddish macule
appearing in early syphilis chiefly on chest abdomen and back.
Macule resembling those of leucoderma and met with about neck in
young in early period.
In secondary syphilis there are wide spread macular rash in palm
and later papular eruption.
Rubric; Skin ,Syphilitic
and also in concerned location chapters.
[G] PURPURA.
Large macule or papule of blood under skin, which does not
blanch on pressure. It is an immune complex disease caused by
type III hypersensitivity reaction.
Histology shows vascularity involving small blood vessels
C/F :Purpuric rash on extensor surface of
forearm,elbows,bottocks ,leg etc. Abdominal colic, vomiting,poly
arthritis,polyarthralgia.
Representations of pupura are two types in Kent’s repertory
1] Purura miliaris and
2] Purpura sanilis.
1] PURPURA MILIARIS
Purpura associated with blockage of sweat glands. It is an
inflammatory disease of disease of skin characterized by redness
,eruption, burning ,itching and release of sweat in abnormal
ways(by eruption of vesicle) due to blockage of sweat gland.
2] PURPURA SANILIS
Chronic disorder of elderly old people above 70 yrs. Pruritic
and ecchymotic spots occurs on extensor aspect of forearm which
arise spontaneously after an unnoticed trauma.
Purpura is due to traction injury to small capillaries of dermis
due to loss of dermal collagen and subcutaneous fat.
Rubric; Skin ,Purpura,sanilis.
H] NAEVUS.
Developmental anomalies consisting of immature melanocytes in
abnormal number.
Two types congenital and acquired
Rubric; Skin, Naevus.
I] LENTIGO MALIGNA. (Hutchinson's freckle)
It is a slowly progressive premalignant disorder of melanocytes
in which malignant melanoma often devolop.Occures in exposed
part of face. Lesion is a pigmented macule with well-defined,
rounded polycystic edges, which may up to 5cms diameter.
Rubric; Skin, Discoloration, liver spots,
Brown.
[J] LEUCODERMA.
White or light pink macules due to destruction of melanocytes.
Rubric; Skin, Discoloration ,pale.
[K] ROSEOLA (Skin eruption without catarrh)
This condition occurs in epidemic form. Eruption preceded
febrile symptoms. The rashes are rose in color. When not in
epidemic form cause is derangement of digestive system.
Other causes;
Sudden changes in temperature
Violent exercise,
Taking cold when over heated.
Two types Idiopathic and Symptomatic
Idiopathic form seen in infants
In Symptomatic erythema develop in the course of acute disease.
Rubric; Skin, Eruption, roseola.
2] VESICLE
Circumscribed elevation of skin < o.5 cm diameter containg
fluid. It is a small elevation of hoary layer of epidermis.
Rubric; Skin, eruption, vesicle.
CONDITIONS: -
[A] ECZEMA (DERMATITIS)
A group of disorder characterized by the process of inflammation
of the skin in which the main focus of damage is in the
epidermis.
Causes: -
Direct injury from toxic substances,
Mechanical trauma,
Immunological reactions.
Common verities of eczema
a) Atopic dermatitis,
b) Seborrhic dermatitis,
c) Descoid eczema,etc.
INTERTRIGO
In some cases the exudation may not be abundant enough to raise
the epidermis in to vesicle, but only loosens it, and the
epidermis actually thrown off leaving a raw, moist surface
called Intertrigo.
Rubric; skin,Intertrigo.
[B] ERYSEPELAS.
Acute febrile disease characterized by peculiar infection of
the skin with enlargement of lymph nodes Caused by Beta
heamolytic streptococci.
C/F :Sudden onset of a well marginated painful and swollen
erythematous area usually of face and lower limbs. Phlegmonous
erysipelas affects the skin in its Whole thickness and
subcutaneous cellular tissue.
Rubric: - skin, erysipelas
[C] HERPES
Vesicular eruption mainly caused by viral infection like Herpes
zoster,herpes simplex, chicken pox etc.
Rubric; Skin, eruption,Herpatic.
1) HERPES ZOSTER.
Caused by DNA virus. Mostly affects immunocompramised patients.
This condition is due to reactivation of virus that has been
sitting latent in a posterior root ganglion of spinal nerves.
If some one with out immunity to chicken pox contact with
patient having shingles that may will develop chicken pox.
C/F :Paresthesia and pain in the distribution of one or more
dermatomes.
Common sites;
Branches of trigeminal nerve.
Rubric;
Skin, eruption, Herpetic, Zoster.
2) VARICELLA (chicken pox)
Rubric; Skin, eruption, chicken pox.
3) HERPES SIMPLEX
Caused by DNA virus, two antigenic varieties, Type I & II.
Type I mainly affects face and oropharynx.
Type II affects genitalia.
Rubric; Type I . Face, eruption, herpetic, lips about.
Type II Genitalia eruption, penis, vesicle.
[D] RING WORM (TINEA INFECTION)
It is a dermatophytic infection. Three groups are there,
a) Trichophyton,
b) Epidermophyton,
c) Microsporon.
C/F Based on the site affected tinea is classified under several
headings
a) Tinea corporis. Tinea of the body and limbs. Pruritic red
round well-marginated patches are seen at the site affected
b) Tinea cruris or groin ringworm.
Common in young men, well defined itchy, red, scaling patches
occurring asymmetrically on the medial aspect of both groin.
c) Tinea pedis ,Affects feet.
d) Tinea mannum,This variety is less common affects one
palm.Palm red and dry with silvery scales.
e) Tinea capitis,Affects scalp, pink scaly patches on the scalp.
f) Tinea ungium,Affects nail plate and nail bed, frequent in
finger nail than toe nail.
Rubric; Skin,eruption,herpetic,circinate.
E] IMPETIGO
CONTAGIOSA
It is a contagious superficial skin infection caused by staphylo
coccus aurius. Mostly a disorder of pre pubertal children.
Characterised by mild pyrexial symptoms followed by one or more
vesicle ,this slowly enlarge , but soon dry in to thin light
yellow scabs.
Rubric; Skin, eruption, impetigo.
F] SCABIES.
Due to infection with human scabies mite [acarus-hominis or
sarcoptus scabie] an obligate parasite. Female parasite lives in
the stratum corneum. Severe itching and characteristic
eczematous rash caused by the invasion of mite. As a result of
the affected individual become sensitive to the waste product of
mite.
C/F :Intense itching, vesicles are seen but excoriation are much
more frequently observed. Prurigo like papule Scaling etc.
Common sites; Palm,interdigital area of fingers,fluxeral
creases, elbows etc.
Rubric; Skin, eruption, scabies.
Extremities, Eruption, elbow, bends of scabies
Extremities, eruption, knee, hollow of scabies.
G] SUDAMINA
Little round vesicle, produced by distension of the cutis by
sweat ,and therefore seated at the orifices of sweat follicle
When the vesicle may be attended with inflammation termed as
miliaria. Prickly heat is likewise a miliaria.
Rubric; Skin, eruption, vesicle, sudamina.
3] BULLA
Circumscribed elevation of skin > 0.5 cm diameter containg
fluid.
Erysipelas
Rubric; Erysipelas.
b) LEPROSY
Caused by mycobacterium lepre large bullae are seen usually
solitary
Disease manifest in three forms Macular, tubercular and
anesthetic.
In Macular there is brownish discoloration of various size and
number.
In tubercular form development of tubercle in various parts of
body. In anesthetic form bullae develop usually solitary
persists for short time leaves behind discoloration and becomes
anesthetic.
c) PEMPHIGUS (Pompolyx)
In this type of diseases blistering is due to Loosening of
desmosal links between epidermal cells caused by immunological
attack.
There are several types important one is Pemphigus vulgaris,
lesions are thin walled delicate blisters usually rapidly
ruptures and erode.
Rubric; Skin, eruption, pemphigus.
d) RUPIA: -
Late malignant manifestation of syphilis. Bullai containing
purulant,reddish mater which gradually dries up and form thick
dark crusts underneath the crust, matter continues to form which
again dries up and consequently raise the center.
Rubric; Skin ,eruption,rupia.
PUSTULE
An elevation of epidermis by purulent exudation.
a) ACNE
One of the commonest skin disorders. It is a disorder of hair
bearing skin in which hair follicle develop obstructing horny
plugs( comidones) as a result of which inflammation later
develop around the obstructed air follicle, causing tissue
destruction and scar formation. Earliest feature of the disorder
is increased rate of sebum secretion making the skin greasy.
Rubric; Face, eruption, Acne.
b) ECTHYMA
Isolated large pustule up on a red swollen surface. Pustule
develops in to the size of a pea. Seen in extremities, on the
seat, chest, neck etc.
In tropical and subtropical areas impetigo like disorder is
spread by flies and bite of arthropods. This is more destructive
and produce deeper, oozing and crusted sores and is caused by
Beta haemolytic streptococci
Rubric; Skin, eruption, ecthyma.
c) FURUNCLES (Boil)
Infection of the hair follicle caused by
staphylococcal aurious.
CARBUNCLE; It is large 3-4 cms diameter and represent
infection of hair follicles.
Rubric: - Skin, eruption, boil.
d) ECZEMA;
Rubric; Skin, eruption, eczema.
PAPULE
Small solid elevation of the skin <0.5 cm diameter.
a) Acne
b) Erythema multiforme.
c) Eczema.
d) Lichen plannus.
LICHEN PLANNUS.
Inflammatory disorder of skin of unknown origin but with an
immunopathogenic component. It is characterized by eruption of
variable extent by typical mauve or pink flat topped itchy
papule.
Common sites,
Front of the wrist,
Skin of lower limb, trunk, and mucosae are affected in 30 %
(mouth)
Rubric; Chest,eruption,like ,lichen plannus.
LICHEN SIMPLEX.
This is a disorder localized to one or more sites. It is
characterized by intense pruritus and exaggerated skin markings.
Sites; Medial aspect of the ankle, back of scalp, extensor
ascept of wrist and forearm.
Seen in tense anxious middle-aged subjects.
Rubric; Chest, eruption, like lichen plannus.
LUPUS.
Skin, eruption,lupus.
MILIUM
Affection characterized by the appearance of minute white or
pearly papule.
It is usually clustered about the eyes, upper and lower eye lid.
Common in women.
Rubric; no direct rubric.
Eye, eruption, lids on.
MOLLUSCUM
CONTAGIOSM
Common infection of skin caused by virus of the poxvirus
group. Pink or skin colored umbulicated papule.
Rubric; no direct rubric.
PRURIGO
Flat papule, which have same color of surrounding skin. When
broken they discharge a small drop of clear fluid with intense
itching.
Aetiology; want of personal hygiene.
RUBIOLA (MEASLES)
Red papule covering the entire surface of skin and
accompanied with febrile symptoms.
Rubric;Skin;eruption,measles.
SYPHILIS
Generalized reddish or copper coloured, may degenerate in to
pustule.
URTICARIA (NETTLE RASH, WHEAL)
Common disorder occurs as a result of histamine release from
mast cells in the skin and are often, though not invariably,
caused by allergic hypersensitivity. Type 1 hypersensitivity
Reaction.
C/F
Itchy red papule and plaque of variable size
Rubric; Skin,eruption ,urticaria
VERIETIES;
1) COLD URTICARIA
After exposure to cold.
Rubric; Urticaria, cold air in,
Cold bath after.
2) PRESSURE URTICARIA
After pressure on skin.
Rubric; Urticaria, scratching after.
3) DERMOGRAPHISM
Urticaria mark when skin is rubbed firmly.
Rubric; Urticaria, scratching after.
4) SOLAR URTICARIA
When exposure to sun.
Rubric; Urticaria, sun exposure to.
5) CHOLINERGIC URTICARIA
Irritation small urticarial spots develop after exercise or hot
bath.
Stimuli that evoke sweating from the postganglionic
cholinegically enervated sweat glands
Rubric; Urticaria, warmth and exercise
Excessive violent after.
TUBERCLE
Solid elevation of skin larger than papule.
a) Acne
b) Fibroma
Tumors of varied size and form which takes their origin from
dermal or sub dermal tissues which are single or multiple.
Rubric; Skin, indutarion, nodules etc.
c) Lentigo maligna
d) Leprosy
Reddish brown tubercle on the forehead, ear etc.
Rubric; Skin, eruption, tubercle, lepros.
e) Lupus; Solitary or few reddish brown tubercles terminate by
ulceration.
f) Syphilis
Copper coloured tubercle terminating with suppuration, in early
syphilis lesions are numerous, in late syphilis number of
lesions are limited.
Rubric; Skin, eruption, tubercle, syphilitic.
g) Morphoea;
It is localized scleroderma,a chronic cutaneous affection,
characterized by appearance of one or more discrete spots or
patches, usually isolated and round in form. It is pink in
colour and slightly elevated when hyperaemic and hypertrophied
later become whitish ,anaemic,atrophic and depressed.
Pathology; Generalized replacement of the subcutaneous fat with
new collagen, which has pale homogeneous appearance. Belong to
immunologically mediated skin diseases.
SCALES
Collection of cell of stratum corneum, due to disturbances
in the formation of stratum corneum.(keratinisation)
When scales are small in size and loosely attached ,like a fine
powder or meal scattered over surface called Farinaceous.
When scales are large ,thick ,heaped up and firmly attached
called Farinaceous.
CONDITIONS;
a) Icthyosis
The word derived from Greek word Icthyos that means fish.
It is a generalized non inflammatory disorder of keratinisation
and implies a congenital origin
Skin is rough and dry covered with thickened and exfoliating
cuticle like scales.
Rubric; Skin, eruption, scaly.
b) Pityriasis verscicolar
Caused by yiest like micro organism Pityrio sporum ovale (malazezia
fur fur). It is common in young adults. It causes brownish
slightly scaly macules over front and back of upper trunk. In
dark skined individuals lesions are hypo pigmented.
Rubric; Skin ,eruption, scaly.
c) Psoriasis
Common genetically determined inflammatory skin disorder of
unknown origin.Charecterised by well demarcated raised scaly
patches,localised to extensor surface.affction commences in
small red somewhat red elevated roundish spots like drops
covered by dry oblong white scales called - Psoriasis guttata.
When the spots are increasing in number, they coalesces to form
large irregular surface, which covered with scales of various
thickness and adhesiveness called - Psoriasis diffusa.
They some times accumulate in round patches, while on the
periphery new spots still appear, and those in the center dries
up give rise to circular eruption called - Psoriasis annulata.
Several such circles join together, their peripheral line broken
off by already healed of center and now they forms various
figures, parts of circle ,straight line etc. called - Psoriasis
gyrata.
In some cases the morbid process continue for a long time and
Causes skin to become thickened, rigid and cracked,this takes
places in diffuse irregular forms called - Psoriasis inveterta.
These names do not indicate different verities but form and
stages of same cutaneous manifestation.
Rubric; Skin, eruption, psoriasis.
Old terminologies used in skin chapter;
Pocks; Skin, eruption, pocks.
It is a pustule in the eruptive disease. (Smallpox)
Scarletina; Acute infectious and contagious disease
characterized by diffuse scarlet eruption.
Gritty; Skin, eruption, gritty.
Eruptions like hard sharp granules as if sand.
Coppery; Reddish
Blotches; Term to denote pigmented or erythematous
lesions
Phagedenic; An ulcer that rapidly spreads peripherally
destroying the tissues as it increase in size.
References:
RAUES
PATHOLOGY
SKIN DISEASES BY DOUGLAS
ROXBERGH'S COMMON SKIN DISEASES BY RONALD MARKS
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